Conclusive evidence that NSAIDs side effects are worse than previously thought is scary news for millions of American arthritis sufferers who depend on these drugs for chronic pain relief. Non-steroidal
anti-inflammatory drugs (NSAIDs) include household names like Advil, Motrin, Aleve and Celebrex. Studies now link all non-aspirin NSAIDs to strokes and cardiac arrest, yet consumers are often unaware of these and other health risks, according to the Food and Drug Administration (FDA).
Growing in the shadows of this “silent epidemic” is increased arthritis consumer choice for drug-free natural pain relief supplements, especially those containing the herb Boswellia and natural glucosamine.
Traditionally, NSAIDs side effects of GI bleeding, ulcers and liver failure have long been documented for causing 100,000 hospitalizations and 17,000 deaths annually in the U.S. Yet the toxic effects of this medical predicament have been given scant publicity. No one appears to be tracking the numbers, leaving many physicians and most patients unaware of the magnitude of the problem, according to a 1999 study in The New England Journal of Medicine.1
The risk from NSAIDs of heart attack and stroke, either of which can lead to death, was initially addressed by the FDA in 2005 in the Boxed
Warning and Warnings and Precautions section of prescription drug labels.
Influenced by mounting evidence from subsequent studies concerning NSAIDs side effects, the FDA made those warnings much stronger on July 9, 2015 for all non-prescription and prescription non aspirin NSAID labels.2. The updated heart-related warnings included, but are not limited to, the following:.
Natural pain management is nothing new. Nature's medicine cabinet has contained the answers for pain relief for centuries. There are many botanical and herbal substances that have proven effective, safe and free of NSAIDs side effects.
The herbs boswellia, menthol and safflower are at the forefront of natural anti-inflammatory remedies. They are well-studied and researched. They have a long history of safely and effectiveness when prescribed for pain relief.
Here are three trusted high quality natural products helpful in attaining pain relief from arthritis, joint pain, injury or surgery:
For complete background information and our personal testimonies on each, click on the following link: Three natural pain products.
NSAIDs side effects accounts for much of the motivation for replacing these painkillers with natural products. With millions of people using medicinal plants worldwide, the market of herbal supplements is witnessing a steady growth. Recent data indicate that in 2012, 17.9 percent of all U.S. adults used botanical supplements In Germany, 90 percent of the people use natural medicines at some time during their life and over 50 percent of the population has done so in other European countries.
Thus, the global market for herbal dietary supplements or phytomedicines, estimated at approximately $60 billion U.S. in 2000, increased dramatically to over $100 billion U.S. by 2017.
Dietary supplements are not regulated in the U.S. the same as pharmaceutical drugs. China and India are the primary sources of raw ingredients. Some manufacturers are not re-testing these substances to ensure purity and accuracy of composition. Others are conducting one cursory test only. This lack of oversight has created an industry where not all supplements are equal. Clinical testing for efficacy is also not an industry requirement. Few companies incur the extra production expense to threaten profitability in a highly competitive market.
The ease of entry into the industry has created a window for unscrupulous opportunists and rogue players. Illegal, tainted and adulterated supplements have increasingly entered the marketplace. Episodes of contamination with insecticides, pesticides, synthetic drugs, heavy metals, and substituting one plant for another either purposefully or through mis-identification are now being discovered.
These occurrences increase concerns about the safety, effectiveness and quality of herbal products found on the store shelves or websites of sellers. If you want to eliminate NSAIDs side effects by"going natural", be certain you're buying high quality supplements that won't waste your money. The featured and most trusted manufacturer we have found is recommended at the end of this report.
Over-the-counter and prescription painkiller drugs are often used inappropriately and there’s a substantial number of people who are not aware of the potential side effects, according to a study published in the November 2005 issue of the Journal of Rheu-matology.5
The study, People Unaware of Harmful Effects of Painkillers, is the first to look at the characteristics, attitudes and behaviors of the population who frequently use non-prescription and prescription NSAIDs.
“This study shows just how common these medications are used and highlights the lack of insight into their potential dangers,” said C. Mel Wilcox, MD, lead study author from the University of Alabama at Birmingham. “The findings paint a clear picture of the need for patient and physician education efforts and interventions to help prevent un-necessary complications from painkillers.”
More than half (fifty-four percent) of the 807 people surveyed in the study were not aware of the potential side effects of these drugs and 18 percent had previously expe-rienced side effects. Those who used over-the-counter painkillers commonly experi-enced side effects such as stomach pain, internal bleeding and ulcers.
Nearly 30 percent of these people did not consider themselves at risk for any NSAIDs side effects associated with painkiller use. The study found similar numbers in people who exclusively used prescription painkillers.
The above study was supported by the American Gastroenterological Association (AGA), which estimates that every day more than 36 million people take over-the-counter and prescrip-tion NSAIDs for pain relief, headaches and arthritis, with nearly 25 percent exceeding the rec-ommended dosage.5
The AGA observed that long-term use of NSAIDs in high doses can provide great benefit in terms of anti-inflammatory effects, pain relief and cardio-protective effects (with aspirin only) but the risk can be great.
With increased dosage, there’s increased risk of gastrointestinal complications ranging from stomach pain to ulcers, hemorrhage and severe and potentially deadly gastrointestinal problems.
For many people, pain relievers are wonder drugs, allowing them to carry on with their lives despite disabling arthritis, for instance, and other chronic pain issues. All NSAIDs, whether sold over the counter or by prescription, have potential risks.
The following NSAIDs side effects relate primarily to people who take pain relievers at least several times a week, according to Berkeley Wellness online publication Reducing Pain Reliever Risks:3:
NSAIDs are effective pain-relievers, but they are intended for short-term use. The Cleveland Clinic cautions never use an over-the-counter NSAID continuously for more than three days for fever, and ten days for pain, without talking to your healthcare provider.4
When taking NSAIDs for long periods of time, you should be carefully monitored by a healthcare provider so he or she can monitor NSAIDs side effects, and change treatment protocol, if necessary.
Depending on the NSAID and the condition being treated, some may work within a few hours, while others may take a week or two before most benefit are achieved. For acute muscle injuries, the Cleveland Clinic recommends NSAIDs that work quickly, however, these may need to be taken as often as every four to six hours because of their short action time.
For osteoarthritis and rheumatoid arthritis that require long-term treatment, they usually recommend NSAIDs that need to be taken only once or twice a day. However, it generally takes longer for these drugs to have a therapeutic (healing) effect.
Side effects may occur if you are taking large doses of NSAIDs, or if you are taking them for a long time. Some side effects are mild and go away, while others are more serious and need medical attention.
Please note: The side effects listed below are the most common. All possible side effects are not included. Always contact your healthcare provider if you have questions about a particular medication.
The most frequently reported side effects of NSAIDs are gastrointestinal symptoms, such as:
These side effects can generally be relieved by taking the drug with adequate amounts of food. NSAIDs may also be taken with milk or antacids (such as Maalox® or Mylanta®) to prevent gastrointestinal symptoms.
If the symptoms continue, the NSAID may need to be stopped. You should contact your healthcare provider if the symptoms listed above do not stop after a few days of taking the NSAID with food, milk, or antacids.
If you have any of the following NSAIDs side effects, it is important to call your healthcare provider right away:
NSAIDs can raise blood pressure in some people. Some people with high blood pressure (hypertension) may have to stop taking NSAIDs, if they notice that their blood pressure increases even if they are taking their blood pressure medications and following their diet. If you are taking blood pressure medication, talk to your healthcare provider before taking NSAIDs.
People who have the following conditions or circumstances should not use any type of NSAID until they are first evaluated by their healthcare provider, according to the Cleveland Clinic
Very rarely, a nonsteroidal anti-inflammatory agent can cause a generalized allergic reaction known as anaphylactic shock. If this happens, it usually occurs soon after the person starts taking the NSAID.
The symptoms of this reaction include:
If any of these symptoms occur, call 9-1-1 or have someone drive you to the nearest emergency room immediately. This information is a summary only. It does not contain all information about these medicines. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other healthcare provider.
The above lists of NSAIDS side effects are a source of great
concern to people who suffer with pain. Many have switched to plant-based pain relief supplements because they are safe, clinically-proven to work and virtually side-effect free. However, it's up to the consumer to investigate the standing of the supplement's maker.
The comparative differences of the manufacturer we recommend has earned them the title of #1 natural nutrition company in the U.S. They formulate and produce the three products outlined, in the third paragraph above (Plant-based natural supplements provide safe, effective pain relief alternative).
They are science-based, conduct clinical studies on their products, prove efficacy and ensure purity and safety through their 'beyond organic' philosophy.
Please click this Pain Trio link for more information or to access each product’s buying page.
The threat to your health from NSAIDs side effects is real. Especially if you are a frequent, consistent user of painkillers, or if you have to exceed daily dose limits to manage pain.
1. Wolfe M. MD, Lichtenstein D. MD, and Singh Gurkirpal, MD, "Gastrointestinal Toxicity of Nonsteroidal Anti-inflammatory Drugs", The New England Journal of Medicine, June 17, 1999, Vol. 340, No. 24, pp. 1888-1889
2 Drug Safety Announcement, FDA strengthens warning that non-aspirin NSAIDs can cause heart attacks or strokes. Food & Drug Administration, July 9, 2015. https://www.fda.gov/Drugs/DrugSafety/ucm451800.htm
3 Article: Reducing pain reliever risks; Published August 4, 2015, updated January 2017, Berkeley Wellness. Accessed online May 29, 2018. http://www.berkeleywellness.com/self-care/over-counter-products/article/reducing-pain-reliever-risks
4 Article, Non-steroidal anti-inflammatory medicines (NSAIDs), accessed May 31, 2018, Cleveland Clinic, April 27, 2016.
5 C. Mel Wilcox, MD, People Unaware of Harmful Effects of Painkillers, Journal of Rheumatology, Nov. 2005. Study supported by American Gastroenterology Association (AGA). http://www.sciencedaily.com/releases/2005/11/051121165432.htm
NSAIDs Side Effects Disclaimer: Health statements on this MSAIDs side effects page have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease
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